Pericardial Mesothelioma Treatment

Pericardial Mesothelioma Treatment

Pericardial Mesothelioma is an extremely difficult cancer to treat and presently, all treatment methods used have a poor success rate.  The chances of a patient’s survival depend largely on how early and how aggressively the cancer is treated.  If pericardial mesothelioma is treated when it has fully matured and developed then the chances of survival are very slim and the prognosis for a patient could be only a couple of months.  The latency period of pericardial mesothelioma (30 – 50 years), and its symptoms which are ordinary of other more common diseases such as pneumonia, make it extremely difficult to diagnose and therefore difficult to treat in its early stages.  In this way, a lot of pericardial mesothelioma treatments do not aim to cure patients but instead focus on reducing the symptoms.

Before a patient is treated, a doctor will evaluate him or her, and afterwards decide which treatment method is most suitable for the patient’s situation.  The patient’s age, medical history, general well being and even weight are taken into account before the doctor will decide which of the three treatments are most appropriate.  These treatments are surgery, chemotherapy and radiation therapy.

Mesothelioma treatment options

As with any cancer, treatment for Mesothelioma depends on the location of the cancer, the progression of the disease, the age as well as state of health of the patient.
It is the oncologist who specializes in the disease who will decide on the line of treatment. The disease is difficult to treat and in most cases the prognosis is poor. Treatment options include:

1. If the diagnosis is done in the early stages surgery may be recommended to remove all cancerous tissues. This means thoracoscopy, VATS or video assisted thoracic surgery, mediastinoscopy (used for staging), or laproscopy.  Often, doctors will advise palliative procedures like chest tube drainage and pleurodesis, thoracoscopy and pleurodesis, pleuroperitonial shunt, or pleurectomy, which treat the symptoms of mesothelioma rather than the disease.
2. Radiation is prescribed aggressively for mesothelioma patients and is often given in combination with surgery or in order to control symptoms, palliatively. Research on using radiation therapy using implants or UV light therapy is in progress as traditional radiation therapy damages surrounding healthy tissue.
3. Chemotherapy is an option and around 12-20% of patients respond to the drugs. Anti-cancer drugs destroy cancer cells and prevent their spread. In mesothelioma, chemotherapy is not considered to be curative. The aim is to prevent spread of the disease; shrink the tumor prior to surgery, known as neoadjuvant therapy; to annihilate any remains of the tumor in the body post surgery; and to relieve pain and other discomfort, palliative chemotherapy. Experts recommend prescribing premetrexed along with cisplastin. These drugs have shown positive results and this is now standard care for Mesothelioma not treatable by surgery.